Benzenemethanamine, 4-chloro-α-phenyl-, (αS)-

Benzenemethanamine, 4-chloro-α-phenyl-, (αS)- - Names and Identifiers

Name	(S)-p-Chlorophenyl-phenylMethanaMine
Synonyms	(S)-4-CHLOROBENZHYDRYLAMINE (S)-p-Chlorophenyl-phenylMethanaMine (S)-alpha-(4-Chlorophenyl)benzylamine (S)-(4-chlorophenyl)(phenyl)MethanaMine Benzenemethanamine, 4-chloro-α-phenyl-, (αS)-
CAS	163837-32-9

Benzenemethanamine, 4-chloro-α-phenyl-, (αS)- - Physico-chemical Properties

Molecular Formula	C13H12ClN
Molar Mass	217.69408
Density	1.175±0.06 g/cm3(Predicted)
Boling Point	336.8±27.0 °C(Predicted)
Appearance	Morphological Solid
pKa	8.08±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

Benzenemethanamine, 4-chloro-α-phenyl-, (αS)- - Upstream Downstream Industry

Raw Materials	(E)-4-chlorobenzaldehyde N-tosylimine TRIPHENYLBOROXIN TRIMETHYL(PHENYL)TIN 4-Chlorobenzaldehyde
Downstream Products	(-)-ALPHA-(4-CHLOROPHENYL)BENZYLAMINE (+)-TARTRATE SALT 4-Chlorobenzophenone

Benzenemethanamine, 4-chloro-α-phenyl-, (αS)- - Introduction

(S)-4-chlorophenylphenylmethylamine, also known as (S)-p-chlorophenylphenylmethylamine, is an organic compound. Its molecular formula is C13H12ClN, relative molecular mass is 213.69.

This compound is optically active and has chirality. Its stereoisomer is labeled "(S)". Chemically, it is a colorless to pale yellow crystalline solid, soluble in organic solvents such as chloroform and dimethyl sulfoxide.

(S)-4-chlorophenylmethylamine is widely used in organic synthesis. It can be used as a chiral ligand to participate in chiral catalytic reactions for the synthesis of chiral compounds with pharmaceutical activity.

The method for preparing (S)-4-chlorophenylmethylamine can be achieved by the substitution reaction of aromatic amines. Usually, the target product is finally obtained by reacting p-nitrobenzylamine with a suitable chlorinated hydrocarbon (e. G., 4-chlorofluorobenzene), followed by reduction and standing crystallization.

When using and operating (S)-4-chlorophenylphenylmethylamine, you need to pay attention to its safety. It is a toxic compound that is harmful to the human body and the environment. During use, the safe operation of the chemical laboratory should be observed, and appropriate personal protective equipment should be worn to ensure good ventilation. In addition, should be stored in a dry, cool, ventilated place, away from the fire and other combustible materials.

Last Update：2024-04-09 20:52:54